Publications sorted by topic
Topics
Medicinal & toxic plants, pharmacological activities
Secondary metabolism-plant physiology
Quinolizidine alkaloids (QA)
Antimicrobial peptides (AMPs)
Chemical Ecology-plant-insect interactions
Geophagy
Phytochemistry-pharmacology
Secondary metabolites- Pharmacy & Pharmacology
Secondary metabolites: Cytoxixity (tumor cells, trypanosomes), synergistic activity
C. elegans- Antioxidants, aging, Alzheimer
Ornithology: General, Phylogeny-Phylogeography
Ornithology: Calonectris diomedea
Ornithology: Parasites/infections
Use of the model system C. elegans
C. elegans
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Ayoub IM, O A. Eldahshan, M Roxo, A N B. Singab, M Wink Baicalein 5,6-dimethyl ether from ameliorates oxidative stress and mediates anti-aging and neuroprotective activities in
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Roxo, M., H Peixoto, M Wink Piquiá (Caryocar villosum) exerts neuroprotective effects and delays age-related muscle decline in Caenorhabditis elegans. Submitted for publication
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Zhang S, C Duangjan, T Tencomnao, L Wu, , J Lin Oolonghomobisflavans exert neuroprotective activities in cultured neuronal cells and anti-aging effects in
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Wink, M. Le nématode Caenorhabditis elegans : un organisme modèle pour la recherche sur le viellissement, l'apoptose et en pharmacologie. In press
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Roxo, M., The use of the nematode Caenorhabditis elegans to study antioxidant and longevity promoting plant secondary metabolites. In New Findings from Natural Products. E.Ovidi, T. Karpinski A. Tiezzi ed; Benthambooks; Submitted for publication
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Wink, M. 2022 Current Understanding of Modes of Action of Multicomponent Bioactive Phytochemicals: Potential for Nutraceuticals and Antimicrobials. Annual Review of Food Science and Technology, 2022. 13:6.1–6.23
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Thabit S, H Handoussa, N S. El Sayed, H Breitinger and M Wink 2021. A fruit extract of Styphnolobium japonicum (L.) counteracts oxidative stress and mediates neuroprotection in Caenorhabditis elegans possibly through the SKN-1/Nrf-2 pathway. Phytomedicine
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Duangjan, C.; Rangsinth, P.;Zhang, S.; Gu, X.;.;Tencomnao, T. 2021 Neuroprotective Effects of Glochidion zeylanicum Leaf Extract against H2O2/Glutamate-Induced Toxicity in Cultured Neuronal Cells and A_-Induced Toxicity in Caenorhabditis elegans. Biology , 10, 800. https://doi.org/10.3390/biology10080800
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Duangjan C, P Rangsinth, X Gu, S Zhang, , T Tencomnao. leaf extract protects against glutamate-induced oxidative toxicity in HT22 hippocampal neuronal cells and increases stress resistance in . Frontiers in Nutrition,
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Kittimongkolsuk P , N Pattarachotanant, S Chuchawankul,, and T Tencomnao. , 10,30. https://doi.org/10.3390/biology10010030
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Kittimongkolsuk P, M Roxo, H Li, S Chuchawankul,, and T Tencomnao. enhance stress resistance and extend lifespan in via the DAF-16/FoxO signaling pathway. Pharmaceuticals , 14, 93. https://doi.org/ 10.3390/ph14020093
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Qi Z, H Ji, M Le, H Li, A Wieland, S Bauer, L Liu, , I Herr 2021. Sulforaphane promotes C. elegans longevity and healthspan by DAF-16/DAF-2 insulin/IGF-1 signaling. Aging 13, 2021
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Roxo M, H Peixoto, P Wetterauer, E Lima, Piquiá shells (): a fruit by-product with antioxidant and anti-aging properties in
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Zhang S, C Duangjan, T Tencomnao, J Liu, M Wink, J Lin 2020 Neuroprotective effects of oolong tea extracts against glutamate-induced toxicity in cultured neuronal cells and Aβ-induced toxicity in Caenorhabditis elegans., Food & Function, 2020, 11, 8179 – 8192, DOI: 10.1039/D0FO01072C
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Azevedo B, A M. S. Pereira, M Roxo, M C. Borges, H Peixoto, B W. Bertoni, S H. T. Contini, A Lopes, S C. França and Antioxidant activity of an aqueous leaf extract from Uncaria tomentosa and its major alkaloids mitraphylline and isomitraphylline in Caenorhabditis elegans. Molecules 2019, 24, 3299; doi:10.3390/molecules24183299
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Duangjan C, P Rangsinth, X Gu, and T Tencomnao 2019 leaf extracts exhibit lifespan extending and oxidative stress resistance properties in via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, https://doi.org/10.1016/j.phymed.2019.153061
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Duangjan C, P Rangsinth, X Gu, Tencomnao, 2019 Lifespan extending and oxidative stress resistance properties of a leaf extract from in Oxidative Medicine and Cellular Longevity 2019, doi.org/10.1155/2019/9012396
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Duangjan C, P Rangsinth, X Gu, S Zhang, M Wink, T Tencomnao (2019) Data on the effects of Glochidion zeylanicum leaf extracts in Caenorhabditis elegans. Data in Brief 26, 104461
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Li H, M Roxo, X Cheng, S Zhang, H Cheng, M Wink Pro-oxidant and Lifespan Extension Effects of Caffeine and Related Methylxanthines in . Food Chemistry X1, doi: 10.1016/j.fochx.2019.100005
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Link P, Isoliquiritigenin exerts antioxidant activity in via insulin-like signaling pathway and SKN-1. Phytomedicine 55, 119–124, https://doi.org/10.1016/j.phymed.2018.07.004
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Peixoto H, M Roxo, E Lima, K Valente, M Braun, X Wang, . Bark extract of the Amazonian tree Endopleura uchi (Humiriaceae) extends lifespan and enhances stress resistance in Caenorhabditis elegans. Molecules 24, 915; doi: 10.3390/molecules24050915
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Petruk G, M Roxo, F de Lise, F Mensitieri, E Notomista, , V Izzo, D M Monti. 2019 The marine gram-negative bacterium sp. PP1Y as a potential source of novel metabolites with antioxidant activity. ers 41, 273-28; doi: 10.1007/s10529-018-02636-4
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Rangsinth P, A Prasansuklab, C Duangjan, K Meemon, and T Tencomnao 2019 Leaf extract enhances oxidative stress resistance and prolongs lifespan in BMC Complementary and Alternative Medicine2019, 19:164
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Tawfeek N, M Sobeh, D I Hamdan, N Farrag, M Roxo, A M. El-Shazly and Phenolic compounds from L. and Willd. (Salicaceae) counteract oxidative stress in 2019, 24, 1999; doi:10.3390/molecules241019
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Thabit S, H Handoussa, M Roxo, B Cestari de Azevedo, N SE El Sayed, . Styphnolobium japonicum (L.) Schott Fruits Increase Stress Resistance and Exert Antioxidant Properties in Caenorhabditis elegans and Mouse Models, Molecules 24 (14), 2633
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Heiner F , B. Feistel, . Sideritis scardica extracts inhibit aggregation and toxicity of amyloid-β in Caenorhabditis elegans used as a model for Alzheimer's disease. PeerJ 6:e4683; DOI 10.7717/peerj.4683
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Peixoto H, M Roxo, H Koolen, F da Silva, E Silva, M Braun, X. Wang, Molecules 2018, 23, 534; doi:10.3390/molecules23030534
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Petruk G, I Gifuni, A Illiano, M Roxo, G Pinto, A Amoresano, A Marzocchella, R Piccoli, , G Olivieri, D M Monti Simultaneous production of antioxidants and starch from the microalga ., Algal Research, 34, 164-174; https://doi.org/10.1016/j.algal.2018.07.012
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Thabit SA, H Handoussa, M Roxo,El Sayed, NS, B Cestari de Azevedo, Evaluation of antioxidant and neuroprotective activities of (L.) usingthe model. PeerJ, 6:e5159; Doi: 10.7717/peerj.5159
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Peixoto, H,M Roxo, T Röhrig, E Richling, Anti-aging and antioxidant potential of var. sorbilis: Findings in indicate a new utilization for roasted seeds of guarana. Medicines; , 61; doi:10.3390/medicines4030061
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Link P, K Roth, F Sporer, and Carlina oxide exhibit antioxidant activity and counteracts Aβ toxicity in . Molecules, , 871; doi:10.3390/molecules21070871, 1-10
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Peixoto H, M Roxo, S Krstin, T Röhrig, E Richling, . An anthocyanin-rich extract of Açaí ( Mart.) increases stress resistance and retards aging related markers in . Journal of Agricultural and Food Chemistry, 64, 1283-1290
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Peixoto H, M Roxo, S Krstin, .2016. Anthocyanin-rich extracts of Acai ( Mart.) mediate neuroprotective activities 6, 385–393
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Sobeh, M, E A. El-Hawary, H Peixoto, R M. Labib, H E. Handoussa, A H. El-Khatib, Sharapov. F, T Mahmoud, S Krstin, MW. Linscheid,A Nasser B. Singab, , N A. Ayoub .phenolic secondary metabolites from Sond. (Fabaceae) and demonstration of their antioxidant activities in PeerJ 4:e2404; DOI 10.7717/peerj.2404
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Wang, E., Chlorophyll enhances oxidative stress tolerance in Caenorhabditis elegans and extends its lifespan. PeerJ 4:e1879; DOI 10.7717/peerj.1879
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Link, P., Fu Y, Wetterauer, B. & Extracts of and isoliquiritigenin, one of its compounds, counteract amyloid-beta toxicity in Planta Medica, 81, 357-362.
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Su S. and , 2015 Natural lignans from as antiaging agents in . Phytochemistry, 117, 340-350.
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Abbas, S., 2014. Green Tea extract induces the resistance of against oxidative stress. Antioxidants 3, 129-143
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Rezaizadehnajafi, L., : EPs7630® from increases stress resistance in and enhances life span probably via the DAF-16/FOXO pathway. Phytomedicine, 21, 547–550
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Chen W, Joubert, E., van Wyk, BE, Ameliorative effect of aspalathin from rooibos () on acute oxidative stress in . Phytomedicine 20, 380-386
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Chen W, L. Rezaizadehnajafi, (2013) Influence of resveratrol on oxidative stress resistance and life span in : J Pharmacy and Pharmacology, 65, 682-688
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Chen,W., D. Müller, E. Richling, (2013)nthocyanin-rich purple wheat prolongs the life span of Caenorhabditis elegans probably by activating theDAF-16/FOXO transcription factor.. Journal Agricultural Food Chemistry,
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*Wink, M. Abbas, S. (2012) Epigallocatchin gallate (EGCG) from green Tea (Camellia sinensis) and other natural products mediate stess resistance and slow down aging processes in Caenorhabditis elegans . In: Tea in Health and Disease Prevention, Elsevier pp 1005-1115
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Abbas, S., Epigallocatechin gallate inhibits beta-amyloid oligomerization in Caenorhabditis elegans and affects the daf-2/insulin-like signaling pathway. Phytomedicine, 17, 902-909, 2010
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Abbas, S. Epigallocatechin gallate (EGCG) from green tea (Camellia sinensis) increases lifespan and stress resistance in Caenorhabditis elegans. Planta Medica 75, 216-221, 2009
Hauser, M.-T. and M. Wink: Uptake of alkaloids by latex vesicles and isolated mesophyll vacuoles of Chelidonium majus (Papaveraceae). Z. Naturforschung 45 c, 949-957, 1990
Mende, P. and M. Wink: Uptake of the quinolizidine alkaloid lupanine by protoplasts and isolated vacuoles of suspension-cultured Lupinus polyphyllus Cells. Diffusion or carrier-mediated transport? Journal Plant Physiology 129, 229-242, 1987
Sauerwein, M., Shimomura, K. and M. Wink: Incorporation of 13C-acetate into tropane alkaloids by hairy root cultures of Hyoscyamus albus. Phytochemistry 32, 905-909, 1993
Szenthe, A., Schäfer, H., Hauf, J., Schwend, T. and Wink, M.: Characterisation and expression of monosaccharide transporters in lupins, Lupinus polyphyllus and L. albus, J. Plant Res. 120 pp 697-705, 2007
Wink, M.: Evolution of plant secondary metabolism: In Ecological biochemistry- Environmental and interspecies interactions, G. J. Krauss & D. H. Niess (eds.) Wiley-VCH, 3-12, 2014
Wink, M.: Evolution of plant secondary metabolism: In Ecological biochemistry- Environmental and interspecies interactions, G. J. Krauss & D. H. Niess (eds.) Wiley-VCH, 3-12, 2014
Wink, M.* and P. Waterman: Chemotaxonomy in relation to molecular phylogeny of plants. In: "Biochemistry of plant secondary metabolism" (M. Wink, ed.), Sheffield Academic Press and CRC Press, Annual Plant Reviews, Vol. 2, 300-341, 1999
Wink, M.** (ed.): Biochemistry of plant secondary metabolism, Sheffield Academic Press and CRC Press, Annual Plant Reviews, Vol. 2, 358 pp, 1999
Wink, M.** (ed.): Function of plant secondary metabolites and their exploitation in biotechnology. Sheffield Academic Press and CRC Press, Annual Plant Reviews, Vol. 3, 362 pp, 1999
Wink, M.: Evolution of Secondary Plant Metabolism. Encyclopedia of Life Sciences, ELS John Wiley Sons, Ltd Chichester, 1-12, 2008
Wink, M.: Biochemistry, Physiology and Ecological Function of Secondary Metabolites. Chapter 1, Introduction. Wiley-Blackwell Annual Plant Reviews 40, 1-19, 2010
Wink, M.: Functions and Biotechnology of plant secontary metabolites. Introduction, Chapter 1., Annual Plant Reviews. 39, 1- 20, 2010
Wink, M.: Vom Pfeilgift bis zum Rauschmittel: Sekundärstoffe - die Geheimwaffen der Pflanzen. Biol. Unserer Zeit, 4, (45), 225-235, 2015
Wink, M.*: Compartmentation of secondary metabolites and xenobiotics in plant vacuoles. Adv. Bot. Res. 25, 141-169, 1997
* Wink, M.: Alkaloids - Properties and Determination. The Encyclopedia of Food and Health, Vol. 1, 97-105, 2016
Wink, M.*: The plant vacuole: A multifunctional compartment. J. Exp. Botany, Vol 44, Supplement, 231-246, 1993
Wink, M., Heinen, H.J., Vogt, H. and H.M. Schiebel: Cellular localization of quinolizidine alkaloids by laser desorption mass spectrometry. Plant Cell Reports 3, 230-233, 1984
Wink, M. and P. Lehmann: Wounding- and elicitor induced formation of coloured chalcones and flavans as phytoalexins in Hippeastrum x hortorum. Botanica Acta 109, 412-421, 1996
Wink, M.: Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective. Phytochemistry 64, 3-19, 2003
Wink, M.: Genes of secondary metabolism: Differential expression in plants and in vitro cultures and functional expression in genetically transformed microorganisms. In: Primary and Secondary Metabolism of Plant Cell Cultures (W.G.W. Kurz, ed.), Springer-Verlag Berlin, 239-251, 1989